Hidden Markov Model in Biological Sequence Analysis– A Systematic Review
نویسنده
چکیده
For biological sequence analysis Hidden Markov Model (HMM) have been used widely in many applications. It has provided solution for various biological sequence analysis problems. In this paper, we first elucidate the fundamentals of HMM, biological sequence analysis and description of the most important algorithms of HMM. This paper especially focusing on HMM and its various types like Profile Hidden Markov Models (PHMMs) and Pair Hidden Markov Models (Pair HMM). Then we have discussed the major bioinformatics applications on HMM in biological sequence analysis problem.
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